abstract：BACKGROUND:Gonadal differentiation in the mammalian fetus involves a complex dose-dependent genetic network. Initiation and progression of fetal ovarian and testicular pathways are accompanied by dynamic expression patterns of thousands of genes. We postulate these expression patterns are regulated by small non-coding ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Torley KJ,da Silveira JC,Smith P,Anthony RV,Veeramachaneni DN,Winger QA,Bouma GJ

更新日期：2011-01-11 00:00:00

abstract：BACKGROUND:Adults with polycystic ovary syndrome (PCOS) can have multiple metabolic abnormalities. However, studies in the adolescent population are still limited and these results seem to vary widely. This study was to investigate the metabolic abnormalities in adolescents with PCOS in South China and the potential ri...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Huang J,Ni R,Chen X,Huang L,Mo Y,Yang D

更新日期：2010-11-17 00:00:00

abstract：BACKGROUND:Several medical conditions can affect and disrupt human sexuality. The alteration of sexuality in these medical conditions often hinder effective communication and empathy between the patients and their sexual partners because of cultural attitudes, social norms and negative feelings such as anxiety and guil...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amidu N,Owiredu WK,Woode E,Appiah R,Quaye L,Gyasi-Sarpong CK

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. METHODS:Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Pinto FM,Ravina CG,Subiran N,Cejudo-Román A,Fernández-Sánchez M,Irazusta J,Garrido N,Candenas L

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast cells, free beta-subunit made by multiple primary non-trophoblastic...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cole LA

更新日期：2010-08-24 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF) has special pro-inflammatory roles, affecting the functions of macrophages and lymphocytes and counter-regulating the effects of glucocorticoids on the immune response. The conspicuous expression of MIF during human implantation and early embryonic development als...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Faria MR,Hoshida MS,Ferro EA,Ietta F,Paulesu L,Bevilacqua E

更新日期：2010-08-04 00:00:00

abstract：OBJECTIVES:It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality. Particularly, the molecular targets and pathways involved in early malignant transformation are still not clear. Pro-inflamma...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zhang L,Wang D,Jiang W,Edwards D,Qiu W,Barroilhet LM,Rho JH,Jin L,Seethappan V,Vitonis A,Wang J,Mok SC,Crum C,Cramer DW,Ye B

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:Antagonists of growth hormone-releasing hormone (GHRH) are being developed for the treatment of various human cancers. METHODS:MTT assay was used to test the proliferation of SKOV3 and CaOV3. The splice variant expression of GHRH receptors was examined by RT-PCR. The expression of protein in signal pathway ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Guo J,Schally AV,Zarandi M,Varga J,Leung PC

更新日期：2010-05-28 00:00:00

abstract：BACKGROUND:Septate uterus, one of the most common forms of congenital uterine malformations, negatively affects female reproductive health. METHODS:In a retrospective cohort study, we evaluated the reproductive outcome after hysteroscopic septoplasty in 64 women with septate uterus and primary or secondary infertility...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Nouri K,Ott J,Huber JC,Fischer EM,Stögbauer L,Tempfer CB

更新日期：2010-05-21 00:00:00

abstract：BACKGROUND:We demonstrated that E2 conjugated to BSA (E2BSA) induces a rapid membrane-initiated inhibition of LH secretion followed hours later by a slight increase in LH secretion. Whether these actions of E2BSA are restricted to the pituitary gland and whether the membrane-initiated pathway of E2BSA contributes to th...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Arreguin-Arevalo JA,Ashley RL,Wagenmaker ER,Oakley AE,Karsch FJ,Nett TM

更新日期：2010-05-10 00:00:00

abstract：:Establishment and maintenance of pregnancy in the pig involves intricate communication between the developing conceptuses and the maternal endometrium. This process occurs during trophoblast elongation which is spaciotemporally associated with conceptus synthesis and release of IL1B concomitant with pregnancy-specific...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ross JW,Ashworth MD,Mathew D,Reagan P,Ritchey JW,Hayashi K,Spencer TE,Lucy M,Geisert RD

更新日期：2010-04-28 00:00:00

abstract：BACKGROUND:The study was designed to test the hypothesis that granulosa cell (GC) gene expression response differs between recombinant FSH and human menopausal gonadotropin (hMG) stimulation regimens. METHODS:Females < 35 years-old undergoing IVF for tubal or male factor infertility were prospectively randomized to on...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Brannian J,Eyster K,Mueller BA,Bietz MG,Hansen K

更新日期：2010-03-12 00:00:00

abstract：OBJECTIVES:To report the occurrence of a rare case of a huge benign ovarian tumour (mucinous cystadenoma) in Jazan city, Saudi Arabia. PATIENTS:Our reported case was a middle-aged Saudi woman presented with marked abdominal distension and discomfort at the gynaecology clinic of Jazan General Hospital, Jazan city, Saud...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Kamel RM

更新日期：2010-03-11 00:00:00

abstract：BACKGROUND:In natural cycles, women conceive when intercourse takes place during a six-day period ending on the day of ovulation. The current practice in intrauterine insemination (IUI) cycles is to perform the IUI 24-36 hours after the hCG administration, when the ovulation is already imminent. In this study hCG was a...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Järvelä IY,Tapanainen JS,Martikainen H

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations. METHODS:This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lackner JE,Agarwal A,Mahfouz R,du Plessis SS,Schatzl G

更新日期：2010-02-05 00:00:00

abstract：BACKGROUND:To study the expression of Plexin-B1, Glycodelin, and MMP7 during the menstrual cycle in the endometrium and in the fallopian tube. METHODS:The research included women undergoing hysterectomy, tubal sterilization or salpingo-oophoerectomy. Total RNA from endometrial and fallopian tube tissues was extracted ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Amir M,Romano S,Goldman S,Shalev E

更新日期：2009-12-29 00:00:00

abstract：BACKGROUND:Progesterone plays an important role in the proliferation and differentiation of human endometrial cells (hECs). Large-dose treatment with progesterone has been used for treatment of endometrial proliferative disorders. However, the mechanisms behind remain unknown. METHODS:To investigate the role of cyclin...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Tang L,Zhang Y,Pan H,Luo Q,Zhu XM,Dong MY,Leung PC,Sheng JZ,Huang HF

更新日期：2009-12-07 00:00:00

abstract：BACKGROUND:Anti-thyroid antibodies (ATA), even if not associated with thyroid dysfunction, are suspected to cause poorer outcome of in vitro fertilization (IVF). METHODS:We retrospectively analyzed: (a) the prevalence of ATA in euthyroid infertile women, (b) IVF outcome in euthyroid, ATA+ patients, and (c) the effect ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Revelli A,Casano S,Piane LD,Grassi G,Gennarelli G,Guidetti D,Massobrio M

更新日期：2009-11-27 00:00:00

abstract：BACKGROUND:Leukocytes represent the predominant source of reactive oxygen species both in seminal plasma and in sperm suspensions and have been demonstrated to negatively influence sperm function and fertilization rate in assisted reproduction procedures. Peroxidase test is the standard method recommended by WHO to det...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Ricci G,Perticarari S,Boscolo R,Simeone R,Martinelli M,Fischer-Tamaro L,Guaschino S,Presani G

更新日期：2009-11-19 00:00:00

abstract：BACKGROUND:The purpose of this study was to test the hypothesis that menstruation is associated with a higher concentration of endometrial cells in peritoneal fluid(PF) and with increased white and red blood cell concentration in PF when compared to nonmenstrual phases of the cycle. METHODS:PF was obtained at laparosc...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Bokor A,Debrock S,Drijkoningen M,Goossens W,Fülöp V,D'Hooghe T

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:Dehydroepinadrosterone (DHEA) supplementation improves pregnancy chances in women with diminished ovarian reserve (DOR), by possibly reducing aneuploidy. Since a large majority of spontaneous miscarriages are associated with aneuploidy, one can speculate that DHEA supplementation may also reduce miscarriage ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gleicher N,Ryan E,Weghofer A,Blanco-Mejia S,Barad DH

更新日期：2009-10-07 00:00:00

abstract：BACKGROUND:Despite the clinical outcomes of ovarian stimulation with either GnRH-agonist or GnRH-antagonist analogues for in vitro fertilization (IVF) being well analysed, the effect of analogues on oocyte/embryo quality and embryo development is still not known in detail. The aim of this case-control study was to comp...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Murber A,Fancsovits P,Ledó N,Gilán ZT,Rigó J Jr,Urbancsek J

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:Several kinds of anti-oxidants have drawn a lot of intention for their benefits on vascular protection. In addition, it has been demonstrated that exercise training could improve endothelial function by up-regulating endothelial nitric oxide synthase (eNOS) protein. Therefore, the present study aims to inves...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Eksakulkla S,Suksom D,Siriviriyakul P,Patumraj S

更新日期：2009-09-07 00:00:00

abstract：BACKGROUND:Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors. Factors inducing microlith development may also, therefore, act as susceptibility factors for...

journal_title：Reproductive biology and endocrinology : RB&E

authors： O'Shaughnessy PJ,Monteiro A,Verhoeven G,De Gendt K,Abel MH

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:Wolfram Syndrome (WS) is an autosomal recessive disorder characterised by non-autoimmune diabetes mellitus, optic atrophy, cranial diabetes insipidus and sensorineural deafness. Some reports have described hypogonadism in male WS patients. The aim of our study was to find out whether Wfs1 deficient (Wfs1KO) ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Noormets K,Kõks S,Kavak A,Arend A,Aunapuu M,Keldrimaa A,Vasar E,Tillmann V

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:During the estrous cycle, the rat uterine endometrium undergoes many changes such as cell proliferation and apoptosis. If implantation occurs, stromal cells differentiate into decidual cells and near the end of pregnancy, a second wave of apoptosis occurs. This process called decidual regression, is tightly ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Caron PL,Fréchette-Frigon G,Shooner C,Leblanc V,Asselin E

更新日期：2009-08-05 00:00:00

abstract：:Endometrial carcinoma is the most common neoplasm of the female genital tract, accounting for nearly one half of all gynecologic cancers in the Western world. Although intensive research on pathological phenomena of endometrial cancer is currently going on, but exact cause and biological aspects of this disease are no...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Park DW,Choi KC,MacCalman CD,Leung PC

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:Coordinated differentiation of the endometrial compartments in the second half of the menstrual cycle is a prerequisite for the establishment of pregnancy. Endometrial stromal cells (ESC) decidualize under the influence of ovarian progesterone to accommodate implantation of the blastocyst and support establi...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Samalecos A,Reimann K,Wittmann S,Schulte HM,Brosens JJ,Bamberger AM,Gellersen B

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Brain-derived ectonucleoside triphosphate diphosphohydrolases (NTPDases) have been known as plasma membrane-incorporated enzymes with their ATP-hydrolyzing domain outside of the cell. As such, these enzymes are thought to regulate purinergic intercellular signaling by hydrolyzing ATP to ADP-AMP, thus regulat...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Zsarnovszky A,Bartha T,Frenyo LV,Diano S

更新日期：2009-06-16 00:00:00

abstract：BACKGROUND:Methadone is the therapeutic agent of choice for the treatment of opiate addiction in pregnancy. The co-consumption (heroin, cocaine) which may influence the effects of methadone is frequent. Therefore, the impact of cocaine and heroin on the placental transfer of methadone and the placental tissue was inves...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Malek A,Obrist C,Wenzinger S,von Mandach U

更新日期：2009-06-11 00:00:00

abstract：:Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significa...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Shi L,Wu J

更新日期：2009-06-05 00:00:00

abstract：:Transient receptor potential cation channel, subfamily V, member 6 (TRPV6) is an epithelial Ca2+ channel protein expressed in calcium absorbing organs. In the present study, we investigated the expression and regulation of uterine and placental TRPV6 during gestation in rodents. Uterine TRPV6 peaked at pregnancy day (...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Lee BM,Lee GS,Jung EM,Choi KC,Jeung EB

更新日期：2009-05-21 00:00:00

abstract：BACKGROUND:Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy i...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Serafini PC,Silva ID,Smith GD,Motta EL,Rocha AM,Baracat EC

更新日期：2009-04-19 00:00:00

abstract：BACKGROUND:The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise. METHODS:Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes. RESUL...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Gallo G,Martino G

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:To assess the amount of variability in ovarian follicular growth rate and maximum follicular diameter related to different centers, women and cycles of the same women in a multicenter observational study of follicular growth. METHODS:Secondary analysis of a prospective cohort study from eight centers in Eur...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Mikolajczyk RT,Stanford JB,Ecochard R

更新日期：2008-12-10 00:00:00

abstract：BACKGROUND:To evaluate the relationship between endometrial thickness on day of human chorionic gonadotrophin administration (hCG) and pregnancy outcome in a large number of consecutive in vitro fertilization and embryo transfer (IVF-ET) cycles. METHODS:A retrospective cohort study including all patients who had IVF-E...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Al-Ghamdi A,Coskun S,Al-Hassan S,Al-Rejjal R,Awartani K

更新日期：2008-09-02 00:00:00

abstract：BACKGROUND:High levels of dopamine (DA) were described in human ovary and recently evidence for DA receptors in granulosa and luteal cells has been provided, as well. However, neither the full repertoire of ovarian receptors for DA, nor their specific role, is established. Human granulosa cells (GCs) derived from women...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Rey-Ares V,Lazarov N,Berg D,Berg U,Kunz L,Mayerhofer A

更新日期：2007-10-25 00:00:00

abstract：:A recent reassessment of the phylogenetic affinities of cetaceans makes it timely to compare their placentation with that of the artiodactyls. We studied the placentae of two sympatric species of dolphin from the Amazon River Basin, representing two distinct families. The umbilical cord branched to supply a bilobed al...

journal_title：Reproductive biology and endocrinology : RB&E

authors： da Silva VM,Carter AM,Ambrosio CE,Carvalho AF,Bonatelli M,Lima MC,Miglino MA

更新日期：2007-06-28 00:00:00

abstract：:The present study evaluates the participation of the vagus nerve in pre-pubertal rats with unilateral ovariectomy on puberty onset, and on progesterone, testosterone and estradiol serum levels, and the compensatory responses of the ovary. Unilateral vagotomy did not modify the onset of puberty in unilaterally ovariect...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Morales L,Ricardo B,Bolaños A,Chavira R,Domínguez R

更新日期：2007-06-13 00:00:00

abstract：BACKGROUND:Bovine luteal parenchymal cells express class II major histocompatibility complex (MHC) molecules and stimulate class II MHC-dependent activation of T cells in vitro. The ability of a class II MHC-expressing cell type to elicit a response from T cells in vivo is also dependent on expression of costimulatory ...

journal_title：Reproductive biology and endocrinology : RB&E

authors： Cannon MJ,Davis JS,Pate JL

更新日期：2007-01-31 00:00:00